Knocksense: A local content and recommendations platform

DRDO crafted anti-infection drug to expedite recovery & reduce oxygen dependence!

With its unique ability to detect the affected cells and act on them, 2 DG significantly helps COVID patients.

In a moment of relief, the first stock of DRDO-crafted anti-COVID drug, 2-DG (2-deoxy-D-glucose) was flagged off earlier this week, for COVID affected individuals. Developed by associative efforts of Nuclear Medicine and Allied Sciences (INMAS), a lab of Defence Research and Development Organisation (DRDO) and Dr Reddy's Laboratories (DRL), the first consignment of the drug was made public amidst the esteemed presence of Defence Minister and Health Minister.


How does the drug work?

The drug comes in powder form in a sachet and has to be taken with water. It collects in the cells infected by the virus and prohibits viral development by damaging synthesis and energy production. With its unique ability to detect the affected cells and act on them, 2 DG significantly helps COVID patients. Reports state that the drug reduced the time of recovery and a median difference of 2.5 days was observed in the relaxation of major symptoms.

10,000 doses to distributed across Delhi Hospitals in the first round

At the inaugural function, the medicine was given by the Defence Minister to the Health Minister, who later transferred it to the Institute of Medical Sciences (AIIMS) director Randeep Guleria. As a part of the first round of disbursement, some hospitals across Delhi will receive the drug and a total of 10,000 doses will be distributed. Given the extraordinary situation of the pandemic, the Drugs Controller General of India (DCGI) gave emergency approval for the drug last week.

It is expected that the drug would revamp the process of treatment by aiding the process of a quick recovery for patients under hospital care behind reducing the dependence on oxygen. During the clinical trials, the drug effectively helped a large number of patients and they tested RT-PCR negative soon.

Phase 2 trials for the drug conducted from May to October 2020

The efficacy of the drug was concluded from the phase 2 trials conducted between May and October last year and now, it will be administered to sick patients. During the first wave of accelerated infections, INMAS-DRDO scientists held laboratory experiments with the help of Centre for Cellular and Molecular Biology (CCMB), Hyderabad in April last year. There, it was discovered that the drug is effective in clamping viral development and can work against SARS COV-2.

On the basis of these findings, the Drugs Controller General of India (DCGI) Central Drugs Standard Control Organisation (CDSCO) allowed Phase-II clinical trial of 2- DG in Covid-19 patients in May 2020. Safety and efficacy trials were started by DRDO in association with its industry partner DRL, Hyderabad. Phase-II was held in six hospitals and Phase IIb (dose ranging) clinical trial was organised at 11 hospitals all over the country. after testing the drug on 110 patients, it was found that 2 DG effectively helps in controlling the infection and improving the recovery.

- With inputs from IANS

Kanpur Coronavirus Update: 616 new Covid cases reported in the last 24 hours

After witnessing a slight drop in daily cases on Thursday with 354, Kanpur witnesses a massive surge in the daily tally at 616 fresh cases on Sunday.

Kanpur's covid graph has again shown a sudden spike in the daily tally of cases on Saturday with 887 fresh cases and 616 cases on Sunday. This comes after showing a considerable dip in cases on Thursday, with 354 cases. The active case count of the city now stands at 3671, while the discharges in the industrial city are at 428, with 1 death reported in the last 24 hours.

Keep reading... Show less

All educational institutes in Lucknow & other districts of UP to remain closed till January 30

Considering the rising pile of COVID cases every day, this move ensures the safety of the vulnerable group of children

In line with the accelerating rate of COVID in Lucknow and the entire state, all schools and colleges in Uttar Pradesh will remain closed till January 30. Notably, all educational institutes were directed to discontinue offline classes till January 23, however, as per the order released by the state administration it has now been extended for another week. Read on to know more about the order.

Keep reading... Show less

Government schools in Indore welcome dropouts for skill training

Dropouts in the state can now enrol for skill training programmes at Govt. schools under new RMSA project.

Six government higher secondary schools in the Indore district have been selected to welcome dropouts who have studied up to class 8th. The motive of the project is to upskill youth to make them employable and open better career opportunities. Narendra Jain, Assistant District Project Coordinator of Rashtriya Madhyamik Shiksha Abhiyaan (RMSA), told TOI that the programme will be run as a pilot project this year. Trainers in these education hubs will be guided by the National Skill Development Corporation (NSDC).

Keep reading... Show less

JMC in action to clean water lettuce engulfing a portion of Dravyavati river

Jaipur Municipal Corporation (JMC) has launched a cleanliness campaign to curtail the fast-spreading weed.

A portion of Dravyavati near Ambabari in Jaipur has suffered an onslaught by pistia stratiotes, also called jalkumbhi or water lettuce. The weed is engulfing the portion of the river from all directions at great speed. In a bid to clean the river, Jaipur Municipal Corporation (JMC) has launched a cleanliness campaign to curtail the fast-spreading weed. Sewerage discharge and stinking water can be considered as the major cause for overspread of the weed. Around five years ago, Anansagar Lake was also attacked by this jalkumbhi. The administration worked very hard to remove the weeds but they have returned this season too. However, it wouldn’t have such grave consequences, due to the consistent flow of water in the river.

Keep reading... Show less

Authentic Mughlai on your mind? The Latif's in Lucknow is where you need be!

With the chef who comes from Kakori-the land known for its kebabs, you can be assured of the authenticity of taste at The Latif's

If you wish to turn your love affair with Mughlai cuisine into a brand new sage, delve deep into the delectable delicacies at The Latif's in Lucknow. Seated at Gomti Nagar, this regular-looking restaurant offers an array of authentic Mughlai dishes to choose from. While we know this locality is famous for its high-priced food joints, breaking that clutter is a rather simple outlet- The Latif, with its high quality of food!

With the chef who comes from Kakori-the land known for its kebabs, you can be assured of the authenticity of taste at this food joint. So instead of worrying about the bills, we suggest you think about ways to manage the walk back to your vehicle as the flavourful offerings here are guaranteed to make you end up overeating!

Keep reading... Show less

No respite from winter chills in Lucknow; IMD predicts colder days ahead!

As per the prediction made by the MeT, a 4-degree drop in temperature will be recorded in Uttar Pradesh in the next three days

After experiencing unusually cold weather this week, Lucknow and other cities of Uttar Pradesh are likely to witness a further dip in temperature in the coming days. As per the prediction by the Indian Meteorological Department, Lucknow will not witness any respite from severe cold waves in the next 48 hours. Notably, the MeT has issued a warning in the northern parts of the country regarding the temperature drop expected in the next five days.

Keep reading... Show less

New in Lucknow: Purple Foods is stirring up city's culinary scenes & how!

Purple Foods debut in Lucknow with their one destination, one stop eatery

Does your agenda this weekend include getting a meal and refreshing drinks with friends/family? Does it also include an argument where you can't agree on where to eat because that one guy in your group is always craving for kebabs, and your best friend wants nothing more than a mocktail to beat the day’s blues and you’d rather have a hearty burger and call it a day!

Well, Lucknowites, in that case, we’ve got news for you! Having marked their debut in the city that loves to eat, only last month, Purple Foods is synonymous with the most indulgent and diverse cuisines all under one roof. They are an instant word-of-mouth hit! An exciting eatery shaking up Lucknow’s culinary landscape by merging high-end food, with authentic familial influences and pan-relish cuisine. Turn over the menu to explore a map of taste-bud-Asia.

Keep reading... Show less

Most Read

Headlines

Lucknow

Kanpur

Trending

Jaipur

Indore

Goa

Mumbai